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KMID : 1036820150200040587
Communication Sciences & Disorders
2015 Volume.20 No. 4 p.587 ~ p.595
A Comparison of the Deterioration Characteristics in Verbal Fluency between Amnestic Mild Cognitive Impairment and Vascular Mild Cognitive Impairment
Kim Hae-Yoon

Kang Yeon-Wook
Yu Kyung-Ho
Lee Byung-Chul
Abstract
Objectives: The present study was conducted to examine when verbal fluency is decreased in amnestic multi-domain mild cognitive impairment (MCI) and vascular MCI, and to compare the deterioration characteristics in verbal fluency between amnestic multi-domain MCI and vascular MCI.

Methods: The subjects were 34 normal elderly, 36 with dementia of the Alzheimer type, 39 with vascular dementia, 72 with amnestic multi-domain MCI, and 70 with vascular MCI. The MCI groups were classified into two subgroups, early MCI (0.5-2.0) and late MCI (2.5-4.0), based on the Clinical Dementia Rating-Sum of Boxes. The subjects were given semantic (animal) and phonemic (¤¡, ¤·, ¤µ) fluency tests.

Results: In amnestic multi-domain MCI, semantic fluency showed progressive deterioration from the early amnestic multi-domain MCI to early dementia of the Alzheimer¡¯s type, whereas in vascular MCI it was significantly decreased in the late vascular MCI but maintained in early vascular dementia. In vascular MCI, phonemic fluency had progressive deterioration from the early vascular MCI to early vascular dementia, whereas in amnestic multi-domain MCI it was significantly decreased in the early amnestic multi-domain MCI and maintained in early dementia of the Alzheimer¡¯s type.

Conclusion: These results suggest that the deterioration characteristics of semantic and phonemic fluency are different between amnestic multi-domain MCI and vascular MCI.
KEYWORD
Verbal fluency, Semantic fluency, Phonemic fluency, Mild cognitive impairment, Amnestic mild cognitive impairment, Vascular mild cognitive impairment
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